Coronavirus

[anticlimatic]

I was not doing anything but sharing opinion? Also, FAKE NEWS.

 

[ceecee]

Didn't we start an entire orange man bad thread to get our TDS venting out? Kind of silly to let it keep distracting us from covid19 info/discussions. Stay on topic please.

Ok

Coronavirus: Citing a primary outcome of death, researchers cut chloroquine study short over safety concerns


Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial | Infectious Diseases | JAMA Network Open | JAMA Network

 

[Jaguar]

Coronavirus: Citing a primary outcome of death, researchers cut chloroquine study short over safety concerns


Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial | Infectious Diseases | JAMA Network Open | JAMA Network

MAGA!

You should take it up with Lysol since they apparently feel the crazy your boy spewed last night requires a Public Service Announcement.

Lysol maker warns against injecting disinfectants after Trump floats coronavirus theory - POLITICO

“And then I see the disinfectant, where it knocks it out in a minute. One minute. And is there a way we can do something like that, by injection inside or almost a cleaning?” Trump said. “Because you see it gets in the lungs, and it does a tremendous number on the lungs. So it would be interesting to check that. So you’re going to have to use medical doctors with — but it sounds interesting to me."


Get this lunatic out of the White House. Now.

 

[cascadeco]

I saw this article several days ago, and today's numbers for Ecuador of +11,000+ are probably due to accounting for folks who hadn't been accounted for yet, and might now more accurately reflect what's going on there per the article. ofc it goes without saying that all of the numbers for every country are going to be estimates/much higher in reality, or won't reflect true numbers, but I guess we can at least observe trends and have a rough gauge of how every country is faring.

Coronavirus Crisis In Ecuador May Be Worse Than The Number Show : Goats and Soda : NPR

 

[á´…eparted]

Ok

Coronavirus: Citing a primary outcome of death, researchers cut chloroquine study short over safety concerns


Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial | Infectious Diseases | JAMA Network Open | JAMA Network

It's like I actually knew what I was talking about when I was shouting this "treatment" is bullshit weeks ago.

Imagine that.

 

[á´…eparted]

You've seriously never heard of bleach or alcohol as a disinfectant? I'm not even sure why you're arguing about this, but I've known about that for years. Yes, bleach can be dangerous. But are you telling me you've seriously never heard of alcohol to disinfect a wound?

I'm pretty sure she has become so sick of me bopping her that the goal has gone from trying to argue against me to simply trying to frame me as fundementally wrong on everything. It renders argument attempts sounding... quite rediculous.

 

[Jaguar]

the bullshitter doesn't care if what they say is true or false, but rather only cares whether their listener is persuaded

Sacrilege.

 

[anticlimatic]

Ok Coronavirus: Citing a primary outcome of death, researchers cut chloroquine study short over safety concerns Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial | Infectious Diseases | JAMA Network Open | JAMA Network

Good girl. Much better.

 

[Jaguar]

Bad dog.

 

[anticlimatic]

Get this lunatic out of the White House. Now.

Swing-state Republicans pin virus fallout on Democrats

 

[Julius_Van_Der_Beak]

Rich from someone named after a Pizza corperation.

Huh? You mean Little Caesars? How do you know it wasn't named after Augustus? Anyway, for what it's worth, I hate Pizza Hut and pretty much any chain pizza except for Bertucci's, because I'm a classy bitch.

 

[Jaguar]

Swing-state Republicans pin virus fallout on Democrats

RealClearPolitics - Election 2020 - Michigan: Trump vs. Biden
EXCLUSIVE: Voters in swing states trust governors over Trump on reopening economy, poll finds | TheHill

 

[Maou]

Ultraviolet blood irradiation: Is it time to remember “the cure that time forgot”?

This is the treatment Trump was referring to in the last press conference.

 

[Jonny]

This guy is a dumpster fire...and lucky for him, because if he weren't such a red hot pile of flaming garbage the virus might be able to infect him and spare the rest of us this nonsense going forward.

Trump
There's been a rumor that -- you know, a very nice rumor -- that you go outside in the sun or you have heat and it does have an effect on other viruses. But now we get it from one of the great laboratories of the world, I have to say. Covers a lot more territory than just this. This is probably an easy thing, relatively speaking, for you.

Trump
I would like you to speak to the medical doctors to see if there’s any way that you can apply light and heat to cure. You know? If you could? And maybe you can, maybe you can’t. Again, I say maybe you can, maybe you can’t. I’m not a doctor. But I’m a person that has a good… You know what. Deborah, have you ever heard of that? The heat and the light relative to certain viruses, yes, but relative to this virus?

Dr. Birx
That is a treatment. I mean, certainly fever is a good thing. When you have a fever, it helps your body respond. But, I’ve not seen heat or light as a--

Trump
I think that’s a great thing to look at. Okay?

Philip Rucker
But, essentially, You’re the president and people tuning in to these briefings they want to get information and guidance and want to know what to do. They’re not looking for rumors.

Trump
Hey, Phil. I’m the President and you’re fake news. And you know what I’ll say to you, I’ll say very nicely… I know you well. I know you well because I know the guy, I see what he writes. He’s a total faker. So are you ready? Are you ready? Are you ready? It’s just a suggestion from a brilliant lab by a very, very smart, perhaps brilliant man. He’s talking about sun, he’s talking about heat and you see the numbers. So, that’s it. That’s all I have. I’m just here to present talent. I’m here to present ideas. Because we want ideas to get rid of this thing and if heat is good, and if sunlight is good, that’s a great thing as far as I’m concerned.​

 

[Jaguar]

#imbleachtrumpnow

 

[Jaguar]

Revealed: leader of group peddling bleach as coronavirus 'cure' wrote to Trump this week

The leader of the most prominent group in the US peddling potentially lethal industrial bleach as a “miracle cure” for coronavirus wrote to Donald Trump at the White House this week.

In his letter, Mark Grenon told Trump that chlorine dioxide – a powerful bleach used in industrial processes such as textile manufacturing that can have fatal side-effects when drunk – is “a wonderful detox that can kill 99% of the pathogens in the body”. He added that it “can rid the body of Covid-19”.

A few days after Grenon dispatched his letter, Trump went on national TV at his daily coronavirus briefing at the White House on Thursday and promoted the idea that disinfectant could be used as a treatment for the virus. To the astonishment of medical experts, the US president said that disinfectant “knocks it out in a minute. One minute!”

Revealed: leader of group peddling bleach as coronavirus 'cure' wrote to Trump this week | World news | The Guardian

And who is Mark Grenon, you may ask? A man who calls himself “the archbishop.”

Shameless: The High Priests of Snake Oil Offer Miracle Cures - ABC News
"20/20" undercover investigation tracks the Genesis II Church and its "clergy."

 

[Jonny]

And who is Mark Grenon, you may ask? A man who calls himself “the archbishop.”

Shameless: The High Priests of Snake Oil Offer Miracle Cures - ABC News
"20/20" undercover investigation tracks the Genesis II Church and its "clergy."

This is the reality we all live in now...it beggars belief.

 

[Red Herring]

Ultraviolet blood irradiation: Is it time to remember “the cure that time forgot”?

This is the treatment Trump was referring to in the last press conference.

That - unreviewed - article by a center focused on alternative medicine (i. e. likely bullshit) talks about how phototherapy is an unproven and near-forgotten method (elsewhere you'll read that it is alternative medicine and little better than homoeopathy or howling at the moon) and recommend looking into a possible use in otherwise hopeless cases (i. e. nothing to lose) of multi-drugresistant BACTERIAL infection and life-threatening sepsis.

SARS-COV-2 is a virus.

 

[Maou]

That - unreviewed - article by a center focused on alternative medicine (i. e. likely bullshit) talks about how phototherapy is an unproven and near-forgotten method (elsewhere you'll read that it is alternative medicine and little better than homoeopathy or howling at the moon) and recommend looking into a possible use in otherwise hopeless cases (i. e. nothing to lose) of multi-drugresistant BACTERIAL infection and life-threatening sepsis.

SARS-COV-2 is a virus.

It was used, and still is used by Eastern European nations. It only went out of use in the west due to competition with anti-biotics also being created at the same time. It isn't "homeopathy", and has been tested. Did you even read the article, or did you just dismiss it because I posted it? Also, "Alternative medicine" is essential, especially for treating evolving pathogens, that will eventually make antibiotics obsolete. I also don't understand the whole shitting on possible cures thing. Since there is no current cure for Corona, it should be common sense to review, test, and try out different treatments that might work. Why is that a bad thing? Do you think something has to have 100% success, tried and true for years, before it is ever talked about? A lot of treatments in medicine are not 100% successful.

Abstract
Ultraviolet blood irradiation (UBI) was extensively used in the 1940s and 1950s to treat many diseases including septicemia, pneumonia, tuberculosis, arthritis, asthma and even poliomyelitis. The early studies were carried out by several physicians in USA and published in the American Journal of Surgery. However with the development of antibiotics, the use of UBI declined and it has now been called “the cure that time forgot”. Later studies were mostly performed by Russian workers and in other Eastern countries, and the modern view in Western countries is that UBI remains highly controversial. This review discusses the potential of UBI as an alternative approach to current methods used to treat infections, as an immune-modulating therapy and as a method for normalizing blood parameters. Low and mild doses of UV kill microorganisms by damaging the DNA, while any DNA damage in host cells can be rapidly repaired by DNA repair enzymes. However the use of UBI to treat septicemia cannot be solely due to UV-mediated killing of bacteria in the bloodstream, as only 5–7% of blood volume needs to be treated with UV to produce the optimum benefit, and higher doses can be damaging. There may be some similarities to extracorporeal photopheresis (ECP) using psoralens and UVA irradiation. However there are differences between UBI and ECP in that UBI tends to stimulate the immune system, while ECP tends to be immunosuppressive. With the recent emergence of bacteria that are resistant to all known antibiotics, UBI should be more investigated as an alternative approach to infections, and as an immune-modulating therapy.

 

[á´…eparted]

That - unreviewed - article by a center focused on alternative medicine (i. e. likely bullshit) talks about how phototherapy is an unproven and near-forgotten method (elsewhere you'll read that it is alternative medicine and little better than homoeopathy or howling at the moon) and recommend looking into a possible use in otherwise hopeless cases (i. e. nothing to lose) of multi-drugresistant BACTERIAL infection and life-threatening sepsis.

SARS-COV-2 is a virus.

This is rather a side tangent but there are actually some fairly exciting developments in medicine taking advantage of light, though they have nothing to do that stuff. Some of the most interesting are more for diagnostic purposes in medical imaging. These compounds, known as near-infrared dyes, allow for extremely find levels of detail in tissues that couldn't normally be imaged. Essentially, organic chemists are working on developing new classes of materials that dissolve in aqueous media (or are compatible in aqueous media via some added linker), have a good quantum yield (roughly the percentage of light absorb/emission in its known absorbance/emitted range), and primarily absorb light in the near-infrared range. The reason near-infrared light is chosen is our tissues are actually rather transparent to it allowing light to pass through our body with minimal scattering or absorbance. It's a somewhat narrow window though because water has a lot of absorbance modes in the infrared range. Overall there are a lot of challenges with this.

There are a lot of exciting developments, and some working prototypes. What these will be most useful for is tumor imaging. You can visualize small cappaliry veins at a resolution you haven't been able to achieve. Once the dyes have been made you conjugate them with an antibody or some biological ligand moiety that will bind to the tissues of interest.

I mean, check out this image. This is of a mouse head, the middle image is with shorter waved infrared which tissues too broadly scatter, so you don't get many details even with a good dye. The right image is at a much longer infrared dye (in the "shortwave" range; yeah the name is kinda confusing). MUCH less scattering, and with a good dye you get SO much detail! This has the potential to completely revolutionize medical imaging.

It really shows you how much detail is enabled by these. Ellen Sletten is whom I consider to be the biggest innovator with this right now as she is pushing for shortwave infrared dyes in the 1300nm range (most dyes are less than 1000nm where scattering is a lot higher). The shortwave goal is much more challenging, but with much higher potential. One of the primary issues right now is with solubility. You have to make some pretty big chromophores to lower the absorbance frequency as low as it is. Typically, the lower you make the absorbance frequency the more unstable the molecule is and/or it becomes more reactive or toxic (sometimes significantly so). You can somewhat get around this by repeating chromophore patterns, but they are almost always aromatic rings which render the molecule insoluable in aqueous AND organic media. Finding that sweet spot is like asking little old lady with coke glasses to thread a needle. It is doable though, and people are figuring it out.

Why am I bringing this up? Well, it's just flat out interesting, but also to point out that in order to take advantage of light therapy of any kind... it gets pretty complicated. Biology is complex as fuck. Explaining my example hear illustrates an example of what REAL innovation is. There are SO many little details you need to account for. There are no quick fixes or easy solutions. Also note the example here uses infrared light; it's quite harmless to the body. Ultraviolet? Not so much. That's just, pretty much universally bad for the body, much more so to expose it to internal parts that haven't evolved to tolerate UV exposure like our outer parts are. There are bound to be a ton of unforseen consequences even if it were to kinda sorta almost work.

Like any "treatment" this administration pushes out, it's a complete non-starter on the surface from a scientific angle. So much so that even a lay person can tell it's bullshit.