I think individual differences matter a lot. The most difficult types for me to get along with are the SF types, which I concider my most opposite. In mean girls who verbal harass other people tend to be SF types, but that doesn't mean all SFs are like this. It only means I have had lots of negative experience with this type.
It really comes down to things like how nice the person is and how accepting the person is of those who are different. Fs are supposed to be more conciderate of other people's feelings, but I have met lots of Fs who were mean people. Many Fs tend to place lots of emphasis on their values. If you happen to share the same values as them (or at least the most important ones) they will generally like you and overlook most of your flaws and eccentricties. If you disagree with their values their opinion of you becomes very negative. A couple of times I have had people that I got along really well with untill it became clear that I did not agree with their values and then it got very ugly.
I think most of the time Ss cannot understand Ns. People who study MBTI a lot may be an exception. However, some Ss will accept Ns eccentricities. Sometimes Ss will express admiration to Ns on their original ideas or creative projects. But some Ss will look down upon you for being different. Sometimes they will try to change you to be more "acceptable," i.e. less different, thinking they are helping you by doing it.
I guess this is more about what they think of me than what I think of them, but I can't seperate the two. If people treat me poorly, they are stressful for me to be around and I avoid them when possible. I tend to feel very defensive, but I attempt to be neutral with them. I try to put on a very strong front, not necissarily agressive, but making it clear that I am not going to compromise myself for them.
If they are nice to me, I generally feel okay having conversations with them, even if I don't feel a connection with them. I tend to react by being a little more friendly and do things that don't come easy to me, such as acting sympathetic and listening politely to subjects I have no interest in.
Ilah