I will second Dominion. It was very useful (for awhile) to use to reconnect to my wife during her post partum depression. With numerous expansions, the bakery is near endless. Moreover, experienced players can finish a game on 15 minutes, so you can rapidly start another.
If you are unaware of the entire euro gaming scene, it is pretty good. As mentioned previously, Settlers of Cataan is great, as is Pandemic. Too many to list here but other good ones, depending on your taste, include Ticket To Ride, San Juan, Race to the Galaxy, Alhambra, Fresco, and many many more.
These games are fun, interactive, creative, and replayable.
Much better than watching TV.....
Some games can be played successfully by young children, even, but really fun for adults.