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http://ftp.cs.kun.nl/CSI/CompMath.Found/teasdale.pdf
Journal of Consulting and Clinical Psychology
2004, Vol. 72, No. 1, 31– 40
Copyright 2004 by the American Psychological Association, Inc.
0022-006X/04/$12.00 DOI: 10.1037/0022-006X.72.1.31
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects
S. Helen Ma and John D. Teasdale
Medical Research Council, Cognition and Brain Sciences Unit
Recovered recurrently depressed patients were randomized to treatment as usual (TAU) or TAU plus
mindfulness-based cognitive therapy (MBCT). Replicating previous findings, MBCT reduced relapse
from 78% to 36% in 55 patients with 3 or more previous episodes; but in 18 patients with only 2 (recent)
episodes corresponding figures were 20% and 50%. MBCT was most effective in preventing relapses not
preceded by life events. Relapses were more often associated with significant life events in the 2-episode
group. This group also reported less childhood adversity and later first depression onset than the
3-or-more-episode group, suggesting that these groups represented distinct populations. MBCT is an
effective and efficient way to prevent relapse/recurrence in recovered depressed patients with 3 or more
previous episodes.
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