That sounds like a situation I have with a work colleague, who I believe is ENFX. In the beginning we seemed to get along fine, and I thought she was a very friendly person who was easy to talk to. Of late though, she seems incredibly hypersensitive, and I can say something completely off-the-cuff and meaningless to another colleague (ISTP) - perhaps jokingly on a random subject, perhaps a discussion about how to approach a piece of work - and she'll come storming round the corner (where she sits she can hear our conversations) to yell at me (more like whine, but it feels like a personal attack either way) as though I've said something to personally insult her, even though it's nothing to do with her!! I'm now at the point where I've decided to avoid her as much as possible and treat her in a very neutral way. If she thinks I'm too serious or blunt, so be it. I have wondered if my efficient, 'let's get down to business' manner scares her somewhat. She's not even slightly serious.
I just hate walking on eggshells, and I think that's the problem I have with NFs. At least with SFs we're kind of on a wavelength, so I can make a guess as to when something might be too blunt or insensitive. NFs seem to take offence at completely banal comments. Not all, obviously, but enough to make me feel on edge when talking to one.