Uh, the last one happened with my mother, who is a ESFJ. Her brother is 60 years old, has been seeing another woman spending her wife's money, has threaten her daughters with a knife... and so on. But now he says 'oh nobody loves me and I'll kill myself'. Then my mother was crying in the kitchen about that, and when she told me the news, I just said 'Well, it would be better if he really kills himself, we all could get some rest then'. And she stopped crying, looked me jaw-dropped and yelled 'He's my brother, don't you dare to say that!'. She was angry at me for the rest of the day :\
Or that time with a very religious history teacher, who was telling us that in the middle ages nobody could explain anything via science because it would be against what 'god' says. And then I chuckled and said (too loud) 'well, if you can't understand science, you can always try with faith'. She looked at me, and I'm not sure if she caught my drift... at least my ENTP classmate aided me saying 'I think she's talking about how they felt in that age'.
I don't know if she got really angry at me, but I think she treated me with some coldness for the rest of the year.