Another point, too, is how well they did in college; did they just eek by or did they excel? What have they done since? Even if they did not use their degree specifically for what it's intended, do they show signs of their education in intelligent ways (not simply parroting stuff to sound smart)? I don't believe the only value of a education is practical career options, so I don't look down on those who get a degree in something "useless". If that person finds it enriched their life and mind, then it has value to them and I can appreciate that. People spend money on far more frivolous things.
After all, I have a degree, and while I will not say it was hard for me to do, it certainly took time, effort, and commitment, and I am better off in many ways for doing it. School comes pretty easy to me actually, and I'm no overachiever. I'm one of those people who is book smart, but not street smart, and I wouldn't want to have my kind of intelligence & skills devalued, so I don't do it to others. Not everyone is the bookish type or learns well in a classroom setting. I've known people who I'd even classify as "intellectual" due to their interests and ability to discuss certain topics, but who were not academics types.