For me it's mostly about people. But there are also places which I don't feel comfortable. Specific, rather than general. There are a couple of shops which I don't patronize anymore because the vibes are uncomfortble to me. Nothing overt. Just the general atmosphere.
There are also sites in RL which seem to vibrate with negative energy to me.
I do need a lot of positive behaviors around me to stay at optimum performance and if I don't have enough of that I create it. If I can't succeed in turning negative situations to my comfort I tend to move on.
It's a matter of staying healthy.