I enjoy one-on-one occasionally, but it would be draining if it were consistent (say, more than 20 hours a week or so). I actually find dealing with several people easier if I don't really have to think about what I'm saying (in other words, just greeting them, saying a few things about work and answering a couple of simple questions, and then just going on my way and starting to work).
I'm beginning to think that I really do work better alone. It makes me think I should look more carefully at dealing with computers again. That does seem like it would be easier to deal with long-term, Even though I technically feel more fulfilled by dealing with people, I really don't think I'd be up to it every day.