Outside of positive/negative... there is just the disorder and how to cope. Emphasize what is useful and minimize or change what is not. Just like any other characteristic.
I feel the same way you talk about with Temple Grandin about most self-aggrandizement in general. On the other hand, people on the spectrum tend to face enough social difficulty already without the additional lack of awareness and stigma that accompanies autism. So I do think that society and people with autism would benefit from more education and inclusion.
For what it's worth... if I were in a relationship with someone with autism... and wanted to have children with them - assuming that my understanding that autism is partially hereditary is correct - I wouldn't worry about it. If my child is autistic then I'll raise them the best I can with the most love I can. I would be so happy if any child of mine, autistic or not, turned out anywhere close to as loving and insightful as a friend of mine who is on the spectrum. Given, I know there are much more severe cases that are more akin to medical disorders than processing disorders. Still - that will be up to fate to determine.