As for me.. If my SO is truly an SO, he IS my family, or rather, a part of my family. It's impossible to make me choose between anything and my family, you see. I'll always pick my family. I may not be so loyal if my family wasn't awesome, but they are, so I am. Family definitely comes first.
Some friends I consider to be like family to me, and I would be there for them in a heart beat. But for me, it's inseparable, the concept of people I love and family. Either I care for you and would go to the limits for you, or I don't.