Which city would it be?
I've often heard from people that New York has become an entity in itself and is rather disconnected from... everything, I guess. Or super-connected. Probably both at the same time. The idea of NYC as representative of the US as a whole is a bit outdated to some.
So, pick a city, any city! Just justify your answer Let's have some fun with this -- it doesn't even have to be in the US.