I've gotten Sarah Jessica Parker, Trisha Yearwood (more when she was younger), Roz from Frasier (Peri Gilpin), among others. I don't look exactly like any of them, but I can see some resemblence with each.
Halla, I think your wife looks like Rebecca deMornay, but I could see the Applegate thing in the second pic. It's more of a facial expression thing, maybe? I bet she looks more like her in motion than in pics.