Life is what we make for ourselves - our memories, our experiences, our aspirations for the future... everything we are in action is governed by our state of being - our state of mind, if you'd call it.
The universe is huge, indeed - maybe one day we'll learn to pursue it, and have more of a reason to pride ourselves.
Who are we? Why are we here? What's going on here? The world is huge, but the universe is huger.
We are a species of sentient life. We are probably here because we evolved this way in response to the conditions on Earth, though some would tell you we were created by a deity or left here by aliens. What's going on is that we've reached a point where we're self-aware and want to understand ourselves, what's beyond the known boundaries, and how it all relates to us. And how we should relate to it, how we should react to it, whatever it is.