"How dreadful!" cried Lord Henry. "I can stand brute force, but brute reason is quite unbearable. There is something unfair about its use. It is hitting below the intellect." ~ Oscar Wilde - The picture of Dorian Gray
I don't know. I don't think I'd be any different personally if it happened in my lifetime because 99.9999% of it will probably be trivia that I can't even put into practice.
Maybe my water would be synthesized directly out of my faucet and I get my steamed rice out of a replicator but I don't think much would be different as far as my philosophy goes. I probably wouldn't even realize that 'everything' had been figured out until someone told me.
Then again I'm not really a discovery person when it comes to knowledge - it's just a tool to me. I'd probably be relieved when the process is out of the way for good and I can just go on with experiencing stuff without having to poke at it with my intellectual yardstick stick of scientific measury.
Hopefully flowers will still be pretty and trees will still grow and I will still be a blanket hermit crab in the morning until I get my coffee.
I would say the ultimate point is not knowledge, but more complex being that comes with experience. This can never end because being changes as you connect (or not) on the fly. However, perhaps it is possible that the universe is an undefined boundary and as we learn to perceive differently our recognition of the boundary shifts perpetually.
Man suffers only because he takes seriously what the gods made for fun - Watts