As a toothfairy agnoticist (also known as pedantic atheist) I will have to temporarily accept the working hypothesis that God exists to participate in this discussion.
Now we have to figure out if man is God´s property or his own master (meaning whether a human being has any right of existence of his own as a child would have a right of its own after being thrown into this world by its parents). If we don´t, then He can very well do as He pleases, because we are merely toys of no intrinsic value. If we do have our own value, things change.
Yet we also have to decide if there is such a thing as free will. If there isn´t, once again we are toys. If we are free and He is allknowing but doesn´t intervene, murder, war, etc. are our own dealing; but it still leaves us with natural desasters, floods, etc. Every time one of us gets devoured by a lion, that lion (also part of the creation, whether or not less worthy than us - His supposed favourites - is yet another question to discuss) gets his dinner. Circle of life, bla bla bla. That leaves natural desasters, etc. But once you accept destruents as part of the creation, they too get their free meal.
So via qui-profit-le-crime we come to the conclusion that the all knowing, all-loving God provides for everybody, worms and germs included. He just doesn´t always favour our species. Now why does it have to be connected to pain and suffering? That´s yet another question for another day. Back to the studio.