As Jesus once said, whoever humbles himself shall be exalted. No, Nietzsche responds 1800 years later--whoever humbles himself wants to be exalted.
Moreover, Nietzsche was also right to claim that the more we practice the Christian monkish virtues the more dishonest we become. We befool ourselves into thinking that we are altruistic because we do good for others and not for ourselves, thinking we've given our 'self' up. But we really did not--we are still subtly insisting on others repaying us for our 'generous deeds'. Thus, the more of our 'self' we renounce, the more we will insist on the world taking care of us. And the more we will think we are entitled to. Jesus's prescriptions, without a doubt would have been disastrous. Evil stems from a lack of inner comfort, yet the further we carry through with our self-abnegation mantra, the less comfortable we become and the more evil we get. Scarily enough, contemporaneously, the better we get at presenting ourselves as congenial. As our society tends to mistake altruism for virtue, whilst notoriously failing to acknowledge the impossibility of such an ethical component.
Unless you can refute psychological egoism, 'giving up the self for Jesus' can be no more than a travesty.