Depends on the strength of F/T. Assuming that both are strong I would say that:
Male NF: Earlier can easily find struggles in school socially, but because of being an F can probably find very reliable social security through family/few friends/girlfriend, what have you. Probably might suffer in relationships for being too sensitive, maybe in school and career as well.
Female NT: Biased, but I believe this is worse, I'll just go from personal experience from this. I've been called selfish, autistic, whatever by most of my friends. I lost most of my friends because they are the embodiment of pure F and nothing else, and even me breathing to them was offensive. I've become asexual because I don't have a chance in hell of ever getting a date, nor, after seeing everyone fail in relationships, do I want to try. I know it's a little extreme, but personally I feel like it's worse for whatever you value more. If you value the opposite, I guess it'd say it'd be extremely difficult.