This is interesting. I'll think on it. INTP son, ISTJ husband.
On one site I read that ISTJs are prone to depression and I could see that.
Son has Social Anxiety Disorder.
"No ray of sunshine is ever lost, but the green which it awakes into existence needs time to sprout, and it is not always granted to the sower to see the harvest. All work that is worth anything is done in faith." - Albert Schweitzer
They can be if they piss everyone else off through "no sympathy" and not making personal alliances but the then their own logic is not sound enough to keep them out of danger zones in their lives, people will be burnt out on them and in return not give them any sympathy or help them out.
In other words, if one is going to stand alone without personal alliances or sympathy for others, one must be damned sure they are capable of sailing the boat alone.