I own Fallout 3, and have been getting very excited about Infamous, Prototype, and Red Faction: Guerilla. I'm also kinda infatuated with getting Deadspace, and not very excited but keep hearing good things about Bioshock.
Of the first 3 sandbox games, RFG looks like the most fun plus you can brake/destroy stuff, then Infamous looks pretty cool, and Prototype seems much more violent and difficult.
Has anyone played any of these? Thoughts, reactions, advice?